Prof. Gazit - Skeletal Biotech Lab

Nadav Kimelman-Bleich, PhD; DMD

(Scientist)

Subjects of interest

Ex vivo dynamic tissue culture.

In vivo electroporation for gene delivery.

Scaffolds and bioreactors.

Intervertebral disc regeneration using engineered mesenchymal stem cells .

Publications list:

Kimelman-Bleich N, Kallai I, Lieberman JR, Schwarz EM, Pelled G, Gazit D.
Gene therapy approaches to regenerating bone.
Adv Drug Deliv Rev. (2012) [Online - Ahead of Print]

Sheyn D, Kallai I, Tawackoli W, Cohn Yakubovich D, Oh A, Su S, Da X, Lavi A, Kimelman-Bleich N, Zilberman Y, Li N, Bae H, Gazit Z, Pelled G, Gazit D.
Gene-modified adult stem cells regenerate vertebral bone defect in a rat model.
Mol Pharm, 8(5):1592-601. (2011) [Full text article]

Kimelman-Bleich N, Seliktar D, Kallai I, Helm GA, Gazit Z, Gazit D, Pelled G.
The effect of ex vivo dynamic loading on the osteogenic differentiation of genetically engineered mesenchymal stem cell model.
J Tissue Eng Regen Med, 5(5):384-93. (2011) [Full text article]

Kimelman-Bleich N, Pelled G, Zilberman Y, Kallai I, Mizrahi O, Tawackoli W, Gazit Z, Gazit D.
Targeted Gene-and-host Progenitor Cell Therapy for Nonunion Bone Fracture Repair.
Molecular Therapy, 19(1):53-9. (2011) [Full text article]

Garty S, Kimelman-Bleich N, Hayouka Z, Cohn D, Friedler A, Pelled G, Gazit D.
Peptide-Modified "Smart" Hydrogels and Genetically Engineered Stem Cells for Skeletal Tissue Engineering.
Biomacromolecules 11(6):1516-1526. (2010) [Full text article]

Kimelman-Bleich N, Pelled G, Sheyn D, Kallai I, Zilberman Y, Mizrahi O, Tal Y, Tawackoli W, Gazit Z, Gazit D.
The use of a synthetic oxygen carrier-enriched hydrogel to enhance mesenchymal stem cell-based bone formation in vivo.
Biomaterials 30(27):4639-48. (2009) [Full text article]

Sheyn D, Kimelman-Bleich N, Pelled G, Zilberman Y, Gazit D, Gazit Z.
Ultrasound-based nonviral gene delivery induces bone formation in vivo.
Gene Ther 15(4):257-66. (2008) [Full text article]

Aslan H, Kimelman-Bleich N, Pelled G, Gazit D.
Molecular targets for tendon neoformation.
J Clin Invest 118(2):439-44. (2008) [Full text article]

Gazit Z, Aslan H, Gafni Y, Kimelman N, Pelled G, Gazit D.
Mesenchymal Stem Cells.
In: Atala A, Lanza R, Thomson JA, and Nerem RM (eds.)
Principles of Regenerative Medicine. Elsevier Inc. (2007)

Kimelman N, Pelled G, Helm GA, Huard J, Schwarz EM, Gazit D.
Review: gene- and stem cell-based therapeutics for bone regeneration and repair.
Tissue Eng 13(6):1135-50. (2007) [Full text article]

Kimelman N, Pelled G, Gazit Z, Gazit D.
Applications of gene therapy and adult stem cells in bone bioengineering.
Regenerative Medicine 1(4):549-61. (2006) [Full text article]

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