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Last
Updated:
15-Jan-2012
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Yoram Zilberman, PhD;
DMD
(Scientist)

Email: yoram.zilberman@huji.ac.il
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Subjects of Interest
- Tissue
engineering and gene therapy to bone, cartilage and ligament.
- Microsurgery
and animal models for skeletal defects and disorders.
- Imaging
technologies including:
- Bioluminescence
analysis for molecular
tracking of delivered genes.
- Faxitron
for the fine and precise
analysis of bone and cartilage structure and remodeling.
- MRI
and micro-MRI analysis for bone,
cartilage and ligament.
- Micro-MRI
analysis IN VIVO AND IN VITRO
of INTERVERTEBRAL DISC, tendon and ligament repair.
- In
vivo fibered confocal fluorescent
microscopy.
- Micro-CT
analysis of bone tissue.
- Animals
models and microsurgery.
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Publications list: (recent
five years)
Sheyn D, Kallai I,
Tawackoli W, Cohn Yakubovich D, Oh A, Su S, Da X, Lavi A,
Kimelman-Bleich N, Zilberman Y, Li N, Bae H, Gazit Z, Pelled G, Gazit D. Gene-modified adult stem cells regenerate vertebral bone defect in a rat model. Mol Pharm, 8(5):1592-601.
(2011) [Full text article]
Kimelman-Bleich
N, Pelled
G, Zilberman
Y, Kallai I, Mizrahi O, Tawackoli W, Gazit Z, Gazit D.
Targeted Gene-and-host Progenitor Cell Therapy for Nonunion Bone
Fracture Repair.
Molecular Therapy, 19(1):53-9. (2011) [Full text article]
Sheyn
D,
Rüthemann M, Mizrahi O, Kallai I, Zilberman Y,
Tawackoli W,
Kanim
LE, Zhao L, Bae H, Pelled
G,
Snedeker J, Gazit D.
Genetically
Modified Mesenchymal Stem Cells Induce Mechanically Stable Posterior
Spine Fusion.
Tissue
Eng Part A,
16(12):3679-86. (2010) [Full text article]
Kallai
I, van Lenthe GH, Ruffoni D, Zilberman Y,
Müller R, Pelled
G,
Gazit D.
Quantitative,
structural, and image-based mechanical analysis of nonunion fracture
repaired by genetically engineered mesenchymal stem cells.
J
Biomech 43(12):2315-20. (2010) [Full
text
article]
Saar
G, Zilberman
Y, Shinar H,
Keinan-Adamsky K, Pelled
G,
Gazit D,
Navon G.
Monitoring of the Effect of Intervertebral Disc Nucleus
Pulposus Ablation by MRI.
NMR
in
Biomedicine 23(6):554-62. (2010) [Full
text article]
Pelled
G, Ben Arav A, Hock
C, Reynolds DG,
Yazici C, Zilberman
Y, Gazit
Z, Awad H, Gazit D, Schwarz E.
Direct Gene
Therapy for Bone
Regeneration: Gene Delivery, Animal Models and Outcome
Measures.
Tissue
Eng Part B 16(1):13-20. (2010) [Full
text article]
Kimelman-Bleich
N, Pelled
G, Sheyn D, Kallai
I, Zilberman
Y, Mizrahi O,
Tal Y, Tawackoli W, Gazit Z,
Gazit D.
The use of a
synthetic
oxygen carrier-enriched hydrogel to enhance mesenchymal stem cell-based bone
formation in vivo.
Biomaterials
30(27):4639-48. (2009)
[Full
text article]
Stok
KS, Pelled
G, Zilberman
Y, Kallai I,
Goldhahn J, Gazit D, Muller R.
Revealing the interplay of bone and cartilage in osteoarthritis through
multimodel imaging of murine joints.
Bone
45(3):414-22. (2009) [Full
text article]
Snedeker
JG, Ben-Arav A, Zilberman Y,
Pelled
G,
Gazit D.
Functional
Fibered Confocal Microscopy: a Promising Tool for Assessing Tendon
Regeneration.
Tissue
Eng Part C 15(3):485:491.
(2009) [Full
text article]
Snedeker
JG, Pelled
G, Zilberman
Y, Ben Arav A,
Huber E, Muller R,
Gazit D.
An Analytical Model for Elucidating Tendon Tissue
Structure and Biomechanical Function from in vivo Cellular Confocal
Microscopy Images.
Cells
Tissues Organs
190(2):111-119. (2009) [Full
text article]
Gafni Y, Ptitsyn AA,
Pelled
G, Zilberman
Y, Gimble JM,
Gazit D.
Circadian Rhythm of
Osteocalcin in the Maxillomandibular
Complex.
J Dent Res
88(1):45-50. (2009) [Full
text article]
Steinhardt Y, Aslan H,
Regev E, Zilberman
Y, Kallai I, Gazit D,
Gazit Z.
Maxillofacial-Derived Stem Cells Regenerate Critical
Mandibular Bone Defect.
Tissue Eng Part A
14(11):1763-73. (2008) [Full
text article]
Tai
K, Pelled
G, Sheyn
D, Bershteyn A,
Han L, Kallai
I, Zilberman
Y,
Ortiz C, Gazit D.
Nanobiomechanics
of Repair Bone Regenerated by
Genetically Modified Mesenchymal Stem Cells.
Tissue
Eng
Part A
14(10):1709-20. (2008) [Full
text article]
Zilberman
Y, Gafni Y, Pelled
G,
Gazit Z,
Gazit D.
Bioluminescent
imaging
in bone.
Methods Mol
Biol 455:261-72. (2008) [Full
text
article]
Sheyn
D, Pelled
G, Zilberman
Y, Talasazan F,
Frank JM, Gazit D, Gazit
Z.
Nonvirally
Engineered Porcine Adipose Tissue-Derived
Stem
Cells: Use in Posterior Spinal Fusion.
Stem Cells
26(4):1056-64. (2008) [Full
text article]
Sheyn
D,
Kimelman-Bleich N, Pelled
G, Zilberman
Y, Gazit D, Gazit
Z.
Ultrasound-based
nonviral gene delivery induces bone
formation in
vivo.
Gene Ther
15(4):257-66. (2008) [Full
text article]
Zilberman
Y, Kallai
I, Gafni Y, Pelled
G,
Kossodo
S, Yared W, Gazit
D.
Fluorescence
molecular tomography enables in vivo
visualization and
quantification of nonunion fracture repair induced by genetically
engineered
mesenchymal stem cell.
J
Orthop Res
26(4):522-30. (2008) [Full
text article]
Pelled
G,
Tai K, Sheyn D, Zilberman Y,
Kumbar S, Nair LS, Laurencin CT, Gazit D,
Ortiz C.
Structural
and nanoindentation
studies of stem cell-based tissue-engineered bone.
J
Biomech 40(2):399-411. (2007) [Full
text article]
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