Skeletal Biotech Lab Home Page

Hebrew University

Last Updated:
15-Jan-2012

Zulma Gazit, PhD
(Scientist, Immunologist)

Dr. Zulma Gazit
Email: zulmag@ekmd.huji.ac.il

Subjects of interest

  • Mesenchymal Stem Cells (MSCs): isolation from different tissues and characterization.
  • MSCs as therapeutic platform for Regenerative Medicine.
  • Non viral gene delivery to MSCs as a novel approach for tissue regeneration.

Publications list: (recent five years)

Sheyn D, Kallai I, Tawackoli W, Cohn Yakubovich D, Oh A, Su S, Da X, Lavi A, Kimelman-Bleich N, Zilberman Y, Li N, Bae H, Gazit Z, Pelled G, Gazit D.
Gene-modified adult stem cells regenerate vertebral bone defect in a rat model.
Mol Pharm, 8(5):1592-601. (2011) [Full text article]

Kimelman-Bleich N, Seliktar D, Kallai I, Helm GA, Gazit Z, Gazit D, Pelled G.
The effect of ex vivo dynamic loading on the osteogenic differentiation of genetically engineered mesenchymal stem cell model.
J Tissue Eng Regen Med, 5(5):384-93. (2011) 
[Full text article]

Smith BJ, Sutton GM, Wu X, Yu G, Goh BC, Hebert T, Pelled G, Gazit Z, Gazit D, Butler AA, Gimble JM.
Ovariectomy and genes encoding core circadian regulatory proteins in murine bone.
Osteoporosis International, 22(5):1633-39. [Full text article]

Kallai I, Mizrahi O, Tawackoli W, Gazit Z
, Pelled G, Gazit D.
Micro–Computed Tomography–Based Structural Analysis of Various Bone-Tissue Regeneration Models.
Nature Protocols, 
6(1):105-10. (2011) [Full text article]

Zhang Y, Gazit Z, Pelled G, Gazit D, Vunjak-Novakovic G.
Patterning osteogenesis by inducible gene expression in microfluidic culture systems.

Integrative Biology, 3(1):39-47. (2011) 
[Full text article]

Kimelman-Bleich N, Pelled G, Zilberman Y, Kallai I, Mizrahi O, Tawackoli W, Gazit Z, Gazit D.
Targeted Gene-and-host Progenitor Cell Therapy for Nonunion Bone Fracture Repair.

Molecular Therapy, 
19(1):53-9. (2011) [Full text article]

Pelled G, Ben Arav A, Hock C, Reynolds DG, Yazici C, Zilberman Y, Gazit Z, Awad H, Gazit D, Schwarz E.
Direct Gene Therapy for Bone Regeneration: Gene Delivery, Animal Models and Outcome Measures.
Tissue Eng Part B 16(1):13-20. (2010) [Full text article]

Kimelman-Bleich N, Pelled G, Sheyn D, Kallai I, Zilberman Y, Mizrahi O, Tal Y, Tawackoli W, Gazit Z, Gazit D.
The use of a synthetic oxygen carrier-enriched hydrogel to enhance mesenchymal stem cell-based bone formation in vivo.
Biomaterials 30(27):4639-48. (2009) [Full text article]

Steinhardt Y, Aslan H, Regev E, Zilberman Y, Kallai I, Gazit D, Gazit Z.
Maxillofacial-Derived Stem Cells Regenerate Critical Mandibular Bone Defect.
Tissue Eng Part A 14(11):1763-73. (2008) [Full text article]

Zilberman Y, Gafni Y, Pelled G, Gazit Z, Gazit D.
Bioluminescent imaging in bone.
Methods Mol Biol 455:261-72. (2008) [Full text article]

Sheyn D, Pelled G, Zilberman Y, Talasazan F, Frank JM, Gazit D, Gazit Z.
Nonvirally Engineered Porcine Adipose Tissue-Derived Stem Cells: Use in Posterior Spinal Fusion.
Stem Cells 26(4):1056-64. (2008) [Full text article]

Sheyn D, Kimelman-Bleich N, Pelled G, Zilberman Y, Gazit D, Gazit Z.
Ultrasound-based nonviral gene delivery induces bone formation in vivo.
Gene Ther 15(4):257-66. (2008) [Full text article]

Gazit Z, Aslan H, Gafni Y, Kimelman N, Pelled G, Gazit D.
Mesenchymal Stem Cells.
In: Atala A, Lanza R, Thomson JA, and Nerem RM (eds.)
Principles of Regenerative Medicine. Elsevier Inc. (2007)

Risbud MV, Guttapalli A, Tsai TT, Lee JY, Danielson KG, Vaccaro AR, Albert TJ, Gazit Z, Gazit D, Shapiro IM.
Evidence for skeletal progenitor cells in the degenerate human intervertebral disc.
Spine 32(23):2537-44. (2007) [Full text article]

Kimelman N, Pelled G, Gazit Z, Gazit D.
Applications of gene therapy and adult stem cells in bone bioengineering.
Regenerative Medicine 1(4):549-61. (2006) [Full text article]

Gafni Y, Zilberman Y, Ophir Z, Abramovitch R, Jaffe M, Gazit Z, Domb A, Gazit D.
Design of a filamentous polymeric scaffold for in vivo guided angiogenesis.
Tissue Eng 12(11):3021-34. (2006) [Full text article]

Aslan H, Zilberman Y, Kandel L, Liebergall M, Oskouian RJ, Gazit D, Gazit Z.
Osteogenic differentiation of noncultured immunoisolated bone marrow-derived CD105+ cells.
Stem Cells 24(7):1728-37. (2006) [Full text article]

Aslan H, Zilberman Y, Arbeli V, Sheyn D, Matan Y, Liebergall M, Li JZ, Helm GA, Gazit D, Gazit Z.
Nucleofection-based ex vivo nonviral gene delivery to human stem cells as a platform for tissue regeneration.
Tissue Eng 12(4):877-89. (2006) [Full text article]

Aslan H, Ravid-Amir O, Clancy BM, Rezvankhah S, Pittman D, Pelled G, Turgeman G, Zilberman Y, Gazit Z, Hoffmann A, Gross G, Domany E, Gazit D.
Advanced molecular profiling in vivo detects novel function of dickkopf-3 in the regulation of bone formation.
J Bone Miner Res 21(12):1935-45. (2006) [Full text article]

Prof. Dan Gazit Dr. Zulma Gazit Dr.Gadi Pelled yoram Nadav kimelman Ilan Kallai

Olga

Shimon

Amir Yosi Navaro Lior Ben-Assaf
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