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Oral tuberculosis following autologous bone marrow transplantation for Hodgkin's disease with interleukin-2 and alpha-interferon immunotherapy

Citation:

Toren A, Ackerstein A, Gazit D, Or R, Raveh D, Kupolovicz U, Engelhard D, Nagler A. Oral tuberculosis following autologous bone marrow transplantation for Hodgkin's disease with interleukin-2 and alpha-interferon immunotherapy [Internet]. Bone Marrow Transplant 1996;18(1):209-10. Copy at http://www.tinyurl.com/y4s9p4pa

Abstract:

A patient with Hodgkin's disease (HD) underwent autologous bone marrow transplantation (ABMT). Six months later while receiving interleukin (IL)-2 and alpha-interferon immunotherapy, he developed a painful lesion in his oral cavity with a fistula in the buccal area. Excision biopsy disclosed necrotizing granulomatous inflammation with acid-fast bacillus. The patient received a 9-month course of isoniazide, rifampin and pyrazinamide, and recovered. The possible pathophysiological mechanism is discussed.

Notes:

Toren, A Ackerstein, A Gazit, D Or, R Raveh, D Kupolovicz, U Engelhard, D Nagler, A eng Case Reports England 1996/07/01 Bone Marrow Transplant. 1996 Jul;18(1):209-10.

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