Multiple rib fracture is a challenging condition that may lead to devastating complications, yet there is no regenerative treatment available for patients beyond pain control. The aim of this project is to develop stem cell therapy to heal broken ribs. Our unique approach is based on administrating the cells systemically to patients’ whole body, and targeting the cells to the injured site, rather than direct cell application into the inflamed fractured site. We use similar imaging tools as described above and study whether the proposed treatment improves functional parameters such as pain.